Quality of life, treatment satisfaction, and treatment preference associated with use of a pen device delivering a premixed 70/30 insulin aspart suspension (aspart protamine suspension/soluble aspart) versus alternative treatment strategies.

Interest in intensified insulin therapy has contributed to the increased popularity of alternative insulin delivery systems, including insulin pen delivery devices. Although there have been several studies of patient-reported outcomes associated with insulin pen use (1–6), there has been no adequate assessment of 1) the most advanced devices, pens delivering premixed intermediate-acting and rapidacting analog insulin; 2) the effects of pens for patients previously naı̈ve to insulin; 3) the effects of pens on general quality of life; and 4) what factors contribute to preference for different insulin delivery systems.